Issa Uzabakiriho joined the orphanage in 2002 when he was found on a street. His parents had died while they were moving from Uganda to Rwanda, and he left with his older brother. However, his brother didn't get a chance to join him in the orphanage. He was among the kids who were told to look for a family to foster or adopt them. He was sent to a vocational and training school where he spent 2 years learning to weld. When he was young, he wanted to be either a video producer or a music producer, but he didn't get the chance to become one. He makes a living by translating films from English to Kinyarwanda.

After realizing that education is the key to success, Issa went back to school, but paying school fees was very hard for him. With the help of his brothers and sisters from the orphanage, he finished high school and moved from one home to another, searching for someone he could call family. He met a family at the church where he went to pray on Sundays, but it didn't work out. Currently, he is living independently. Issa said, "I faced challenges throughout my life because I didn't have the opportunity to have parents or a guardian who could show me the realities of life. I worked hard, but I wasn't able to find someone who could support me. If the caregivers or the orphanage staff truly cared about us, it wouldn't have been this hard. We would still be connected and receiving advice from them, checking on how we are doing in life. However, I think they prioritized their salaries. What I can tell everyone who gets a chance to read my story is that they have to love and care for every child as if they were their own. You never know what the future holds. Tomorrow, it could be their child or their relatives who need such kind of help, love, or care."